Aortic thrombosis after DVT and PE in a young COVID-19 patient

Ann Vasc Surg. 2021 Nov:77:79-82. doi: 10.1016/j.avsg.2021.07.005. Epub 2021 Aug 16.

Abstract

A rare case of aortic thrombosis in a young COVID-19 positive patient is presented in this case report. Arterial thrombosis developed despite the administration of anticoagulants for treating DVT and PE. The patient underwent axillobifemoral bypass surgery. Limited surgical surveillance, administered steroids and critical health status resulted in wound site infection and consequent graft removal. Aortic endarterectomy and autovenous-patch plasty were performed after the patient's condition improved. Etiopathogenesis of arterial events in the setting of COVID-19 is not entirely understood. It has been suggested that SARS-CoV-2 infection strongly affects vascular endothelial glycocalyx (VEGLX), causes systemic inflammation - reactive microvascular endotheliosis (SIRME), and consequently results in arterial thrombosis.

Publication types

  • Case Reports

MeSH terms

  • Aorta, Thoracic*
  • Aortic Diseases / diagnosis
  • Aortic Diseases / etiology*
  • Aortic Diseases / surgery
  • COVID-19 / complications*
  • Computed Tomography Angiography
  • Endarterectomy / methods
  • Endovascular Procedures / methods
  • Humans
  • Male
  • Middle Aged
  • Pulmonary Embolism / complications*
  • Pulmonary Embolism / diagnosis
  • Pulmonary Embolism / drug therapy
  • Rare Diseases*
  • SARS-CoV-2
  • Thrombosis / diagnosis
  • Thrombosis / etiology*
  • Venous Thrombosis / complications*
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / drug therapy