Objectives: This study aimed to explore the short-term clinical efficacy and factors influencing low-dose superficial X-ray for treating infantile maxillofacial hemangioma.
Methods: Retrospective analysis was conducted on 161 cases of infants with maxillofacial hemangioma treated with superficial X-ray in the Laser Center of Dermatology Department of Sichuan Provincial People's Hospital from January 2015 to December 2017. Clinical efficacy was analyzed by comparing the photos before and after treatment. Patients were further divided into groups according to different genders, age at the start of treatment, preterm birth or low birth weight, hemangioma site, longest diameter of hemangioma, and type of hemangioma to analyze whether differences existed in clinical efficacy and therapeutic dose between different groups.
Results: Twelve months after the end of treatment, the overall cure rate was 93.8%, and the significant efficiency was 97.5%. The clinical efficacy was related to the age of children at the beginning of treatment and the type of hemangioma (P<0.05). The clinical efficacy of children aged less than or equal to 12 months and superficial hemangioma group was better than that of children aged more than 12 months and deep subtype or mixed hemangioma group, respectively. Therapeutic doses associa-ted with hemangioma treatment with diameter, category, age (P<0.05), diameter greater than or equal to 4 cm hemangioma group, the mixed type or deep in the group, the children older than 12 months hemangioma group, respectively, the dia-meter is less than 4 cm hemangioma, superficial hemangioma group and age less than or equal to 12 months hemangioma total treatment group exposure dose is greater.
Conclusions: Low-dose superficial X-ray is safe and effective for the treatment of infantile maxillofacial hemangioma. Age and type of hemangioma at the time of treatment are the factors influencing therapeutic dose and clinical efficacy.
目的: 探讨低剂量浅层X线治疗婴幼儿颌面部血管瘤的近期临床疗效及影响因素。方法: 回顾性分析2015年1月至2017年12月间于四川省人民医院皮肤科激光中心使用浅层X线治疗的161例婴幼儿颌面部血管瘤患者，通过对比治疗前后照片分析其临床疗效，进一步将患者按照不同性别、治疗开始年龄、出生时是否早产或低体重、血管瘤部位、血管瘤最长直径、血管瘤类型进行分组，分析不同组别间患者的临床疗效及治疗剂量是否具有差异。结果: 治疗结束12月后，患者总体痊愈率93.8%，显效率97.5%。临床疗效与患儿治疗开始年龄及血管瘤类别有关（P<0.05），小于等于12月龄患儿组及浅表型血管瘤组分别较大于12月龄患儿组及深在型或混合型血管瘤组临床疗效更优。治疗剂量与血管瘤直径、类别、治疗开始年龄有关P<0.05），直径大于等于4 cm血管瘤组、混合型或深在型血管瘤组、患儿年龄大于12月血管瘤组分别较直径小于4 cm血管瘤组、浅表型血管瘤组及患儿年龄小于等于12月血管瘤组照射总治疗剂量更大。结论: 低剂量浅层X线治疗婴幼儿颌面部血管瘤安全有效，治疗时患儿年龄及血管瘤类型是治疗剂量及临床疗效的影响因素。.
Keywords: hemangioma; infant; maxillofacial region; superficial X-ray; therapeutic effect.