Predictors of long-term HRQOL following cardiac surgery: a 5-year follow-up study

Health Qual Life Outcomes. 2021 Aug 17;19(1):197. doi: 10.1186/s12955-021-01838-1.

Abstract

Background: The study aimed to evaluate the long-term change of health-related quality of life (HRQOL) and to identify predictors of HRQOL 5 years after cardiac surgery.

Methods: Consecutive adult patients, undergoing elective cardiac surgery were enrolled in the study. HRQOL was measured using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) questionnaire before and 5-years after cardiac surgery. A multivariate latent change modeling approach was used for data analysis.

Results: 210 participants (30.5% female) were reached at 5-year follow-up and included in final data analysis. The study revealed, after controlling for gender effects, a significant long-term positive change, in physical functioning (PF, Mslope = 19.79, p < 0.001), social functioning (SF, Mslope = 17.27, p < 0.001), vitality (VT, Mslope = 6.309, p < 0.001) and mental health (MH, Mslope = 8.40, p < .001) in the total sample. Lower education was associated with an increase in PF (Mslope = 24.09, p < 0.001) and VT (Mslope = 8.39, p < 0.001), more complicated surgery (other than the coronary artery bypass graft (CABG) predicted increase in general health (GH, Mslope = 6.76, p = 0.005). Arrhythmia was a significant predictor for lower pre- and post-operative VT and SF.

Conclusions: Overall HRQOL in our sample improved from baseline to five years postoperatively. Further studies including larger patient groups are needed to confirm these findings.

Keywords: Cardiac surgery; Health-related quality of life; Long-term; Risk factors.

MeSH terms

  • Adult
  • Cardiac Surgical Procedures / psychology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mental Health
  • Quality of Life / psychology*
  • Stroke Volume
  • Surveys and Questionnaires
  • Ventricular Function, Left