Differentiation of autism spectrum disorder and mood or anxiety disorder

Autism. 2022 Jul;26(5):1056-1069. doi: 10.1177/13623613211039673. Epub 2021 Aug 18.

Abstract

Symptoms of mood and anxiety disorders overlap with symptoms of autism spectrum disorder, making the diagnostic process challenging. This study found that a combination of communicational deficits and unusual and/or inappropriate social overtures facilitates differentiation between autism spectrum disorder and mood and anxiety disorders. Furthermore, the results confirm the essential need of a behavioral observation with the Autism Diagnostic Observation Schedule in combination with a full Autism Diagnostic Interview-Revised to support diagnostic decisions.

Keywords: Autism Diagnostic Interview–Revised; Autism Diagnostic Observation Schedule; anxiety disorders; autism spectrum disorder; mood disorder.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Affect
  • Anxiety Disorders / diagnosis
  • Autism Spectrum Disorder* / diagnosis
  • Autistic Disorder* / diagnosis
  • Communication
  • Humans