Coronary artery vasospasm is typically managed through avoidance of triggers and with symptomatic treatments with calcium channel blockers and long-acting nitrates. Here, we report a rare case of medically refractory coronary artery vasospasm associated with genetic predispositions that initially required cardiac autotransplantation followed paradoxically by nicotine for long-term symptomatic control. (Level of Difficulty: Intermediate.).
Keywords: CAV, coronary artery vasospasm; CCB, calcium channel blocker; autonomic modulation; cardiac autotransplantation; coronary artery vasospasm; nicotine.