The erroneous perception of a clinical sign: Cholestasis preceding sepsis mimicking hepatitis in an adolescent patient

Fabrizio Romano; Marisa Molinaro; Susanne Schibli; Philipp Ka Agyeman; Ruth Mari Löllgen

doi:10.1002/ccr3.4578

The erroneous perception of a clinical sign: Cholestasis preceding sepsis mimicking hepatitis in an adolescent patient

Clin Case Rep. 2021 Aug 11;9(8):e04578. doi: 10.1002/ccr3.4578. eCollection 2021 Aug.

Authors

Fabrizio Romano^{1

2}, Marisa Molinaro², Susanne Schibli², Philipp Ka Agyeman², Ruth Mari Löllgen^{1

3

4}

Affiliations

¹ Pediatric Emergency Department Department of Pediatrics, Inselspital Bern University Hospital University of Bern Bern Switzerland.
² Department of Pediatrics, Inselspital Bern University Hospital University of Bern Bern Switzerland.
³ Pediatric Emergency Department Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden.
⁴ Karolinska Institutet Department of Women's and Children's Health Stockholm Sweden.

Abstract

Jaundice should be considered as a first clinical sign preceding severe invasive bacterial infection or sepsis in patients of all ages including childhood and adolescence. Early laboratory investigations and MR imaging studies for osteomyelitis or myositis are paramount to avoid progression to life-threatening sepsis and significant morbidity and mortality.

Keywords: adolescents; children; emergency department; jaundice; sepsis.

Publication types

Case Reports