Prevention of Microvascular Complications of Diabetes

Winston Crasto; Vinod Patel; Melanie J Davies; Kamlesh Khunti

doi:10.1016/j.ecl.2021.05.005

Prevention of Microvascular Complications of Diabetes

Endocrinol Metab Clin North Am. 2021 Sep;50(3):431-455. doi: 10.1016/j.ecl.2021.05.005.

Authors

Winston Crasto¹, Vinod Patel², Melanie J Davies³, Kamlesh Khunti³

Affiliations

¹ Department of Diabetes and Endocrinology, George Eliot Hospitals NHS Trust, College street, Nuneaton CV10 7DJ, UK. Electronic address: winston.crasto@geh.nhs.uk.
² Department of Diabetes and Endocrinology, George Eliot Hospitals NHS Trust, College street, Nuneaton CV10 7DJ, UK; Warwick Medical School, University of Warwick, Coventry, UK.
³ Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK.

PMID: 34399955
DOI: 10.1016/j.ecl.2021.05.005

Abstract

Microvascular complications of diabetes present a significant challenge due to their diverse presentations, significant morbidity, and as strong predictors of cardiovascular disease. Prevention and management strategies should focus on lifestyle modification, education and awareness, systematic screening for early complications, and intensive management of modifiable risk factors. This review discusses the microvascular complications of diabetes, including diabetic retinopathy, diabetic kidney disease, and diabetic neuropathy, and provides best practice clinical care recommendations to guide health care professionals to better manage people with these conditions.

Keywords: Cardiovascular; Diabetes; Diabetic kidney disease; Diabetic neuropathy; Diabetic retinopathy.

Publication types

Review

MeSH terms

Cardiovascular Diseases* / complications
Diabetes Mellitus, Type 2* / complications
Diabetic Nephropathies* / etiology
Diabetic Nephropathies* / prevention & control
Diabetic Neuropathies* / etiology
Diabetic Neuropathies* / prevention & control
Diabetic Retinopathy* / diagnosis
Diabetic Retinopathy* / etiology
Diabetic Retinopathy* / prevention & control
Humans
Risk Factors