The Quest for a DISE Protocol

Otolaryngol Head Neck Surg. 2022 Sep;167(3):590-599. doi: 10.1177/01945998211036645. Epub 2021 Aug 17.

Abstract

Objective: The objective of this quality initiative project was to modify our existing institutional drug-induced sleep endoscopy (DISE) protocol so that the surgeon could consistently determine obstructive breathing patterns while minimizing children's discomfort.

Methods: A quality initiative study utilizing the well-described plan-do-study-act (PDSA) process was conducted at a tertiary hospital for children with polysomnogram-documented obstructive sleep apnea who were undergoing DISE. A 4-point Likert measurement tool was created. Change in each Likert rating with subsequent PDSA cycle was tested with the Wilcoxon rank sum test (Mann-Whitney), and change across all PDSA cycles was tested with the Kruskal-Wallis equality-of-populations rank test.

Results: After a series of 4 PDSA cycles with 81 children, the DISE protocol was streamlined from 14 to 9 steps. There was significant improvement for all aspects of the DISE, with a final overall median rating of 1 (excellent) for intravenous (IV) placement, scope insertion, and anesthesiologist and surgeon satisfaction (P < .01).

Discussion: For sleep surgeons, DISE is quickly becoming what bronchoscopy is to the airway surgeon. Utilizing inhalational agents to obtain IV access and insert the flexible scope in the rapid "on-off" fashion optimizes DISE success regardless of the primary sedation medication and allows ample time for these agents to dissipate.

Implications for practice: Adoption of a DISE protocol that includes nasal premedication and inhalational volatile gases for IV and scope insertion at the onset provides a more predictable level of sedation that is well tolerated by the patient, enabling the otolaryngologist to create an obstructive sleep apnea treatment plan.

Keywords: DISE; PS/QI; child; drug-induced sleep endoscopy; obstructive sleep apnea; quality improvement.

MeSH terms

  • Bronchoscopy
  • Child
  • Endoscopy* / methods
  • Humans
  • Polysomnography / methods
  • Sleep
  • Sleep Apnea, Obstructive* / diagnosis
  • Sleep Apnea, Obstructive* / surgery