COVID-19 Unveiling Brain Calcifications

J Mol Neurosci. 2022 Jan;72(1):25-26. doi: 10.1007/s12031-021-01899-3. Epub 2021 Aug 15.

Abstract

Neurological symptoms in COVID-19 patients have attracted the interest of the scientific community, yet their mechanisms remain unknown. In some circumstances, the presence of neurological manifestations may result in an incidental diagnosis after a detailed investigation. In the present letter, we discuss a case published by Demir et al., in which the diagnosis of COVID-19 enabled the diagnosis of a rare neurological disorder, characterized by bilateral brain calcifications, commonly known by the eponym Fahr's syndrome. In addition, we report a case of primary brain calcifications unveiled by a suspected coronavirus infection.

Keywords: Basal ganglia calcifications; COVID-19; Fahr’s disease; Primary familial brain calcifications.

Publication types

  • Case Reports

MeSH terms

  • Basal Ganglia Diseases / complications
  • Basal Ganglia Diseases / diagnostic imaging*
  • COVID-19 / complications*
  • Calcinosis / complications
  • Calcinosis / diagnostic imaging*
  • Diagnosis, Differential
  • Humans
  • Incidental Findings
  • Male
  • Middle Aged
  • Neurodegenerative Diseases / complications
  • Neurodegenerative Diseases / diagnostic imaging*
  • Neuroimaging*
  • SARS-CoV-2*
  • Seizures / etiology
  • Tomography, X-Ray Computed*

Supplementary concepts

  • Fahr's disease