Cardiac Tumors: JACC CardioOncology State-of-the-Art Review

Sara Tyebally; Daniel Chen; Sanjeev Bhattacharyya; Abdallah Mughrabi; Zeeshan Hussain; Charlotte Manisty; Mark Westwood; Arjun K Ghosh; Avirup Guha

doi:10.1016/j.jaccao.2020.05.009

Cardiac Tumors: JACC CardioOncology State-of-the-Art Review

JACC CardioOncol. 2020 Jun 16;2(2):293-311. doi: 10.1016/j.jaccao.2020.05.009. eCollection 2020 Jun.

Authors

Sara Tyebally¹, Daniel Chen^{1

2}, Sanjeev Bhattacharyya¹, Abdallah Mughrabi³, Zeeshan Hussain⁴, Charlotte Manisty¹, Mark Westwood¹, Arjun K Ghosh^{1

2}, Avirup Guha^{5

6}

Affiliations

¹ Cardiology Department, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.
² Cardio-Oncology Service, University College London Hospital, London, United Kingdom.
³ Jordan University of Science and Technology, Al Ramtha, Irbid, Jordan.
⁴ Division of Cardiology, Loyola University Medical Center, Chicago, Illinois, USA.
⁵ Cardio-Oncology Program, Division of Cardiology, Ohio State University, Columbus, Ohio, USA.
⁶ Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio, USA.

Abstract

Cardiac masses are rare, but remain an important component of cardio-oncology practice. These include benign tumors, malignant tumors (primary and secondary) and tumor-like conditions (e.g., thrombus, Lambl's excrescences, and pericardial cyst). The advent of multimodality imaging has enabled identification of the etiology of cardiac masses in many cases, especially in conjunction with information from clinical settings. This paper provides a comprehensive review of the epidemiology, clinical presentation, imaging, diagnosis, management, and outcomes of cardiac masses.

Keywords: CMR, cardiovascular magnetic resonance imaging; CT, computed tomography; FDG, fluorodeoxyglucose; PCT, primary cardiac tumor; PET, positron emission tomography; RT3DE, real-time 3-dimensional echocardiography; TEE, transesophageal echocardiography; TTE, transthoracic echocardiography; UEA, ultrasound-enhancing agent; cardiac masses; cardiac metastases; cardiac myxoma; cardiac sarcoma; cardiac tumors; papillary fibroelastoma; pericardial cyst; pericardial mesothelioma; pericardial tumors.

Publication types

Review