Takayasu arteritis (TA) is a rare idiopathic vasculitis of large blood vessels. Prevalence is highest in Japan, with predominance in young females. Classic signs and symptoms include limb claudication, decreased/absent distal pulses, vascular bruits, and blood pressure discrepancy between arms. Without treatment, progression leads to mural fibrosis, stenosis, hypertension, thrombus formation, and ischemic changes of surrounding tissue. Takayasu arteritis is usually a clinical and radiographic diagnosis and has a low mortality rate with effective treatment. Here, we present an unexpected case of TA in a 19-year-old black male diagnosed at autopsy. No suggestion of vasculitis was noted during antemortem workup. Takayasu arteritis may be encountered in the forensic setting in cases of sudden death in a young person, especially in the context of an atypical demographic.
Keywords: Autopsy; Differential diagnosis; Forensic pathology; Takayasu arteritis; Vasculitis.
© 2019 The Authors.