Background: Basal ganglia and cerebellum are structurally and functionally connected in animals. In humans, tractography and seed-based functional connectivity have confirmed this cerebellar-striatal relation. Independent component analysis (ICA) showed that both cerebellum and basal ganglia take part in distinct intrinsic networks.
Methods: Probabilistic ICA analysis was applied to the brain images of 15 healthy volunteers during the resting state and using a 3 T MRI.
Results: A spatial map corresponding to dorsal and ventral basal ganglia circuits was also found to be in functional coherence with crus 2, especially with its vermal region.
Conclusion: It is speculated that such cerebellar-basal ganglionic rsFC could reflect structural interconnections traced in animals and explain reward-based activity detected in the cerebellum.
Keywords: Basal ganglia; Cerebellum; Crus 2; Independent component analysis; Resting-state; Vermis.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.