Based on the type-II fuzzy logic, this paper proposes a robust adaptive fault diagnosis and fault-tolerant control (FTC) scheme for multisensor faults in the variable structure hypersonic vehicles with parameter uncertainties. Type-II fuzzy method approximates the original models while eliminating the parameter uncertainties. Hence the sensor faults are detected and isolated by the multiple output residuals and thresholds considering nonlinear approximation errors and disturbance. Based on the fuzzy adaptive augmented observer, the faults and disturbance are all estimated accurately by an improved proportional-differential part. Then a variable structure FTC scheme repairs the faults by the estimation, the fast-varying disturbance is considered in FTC scheme and is compensated by the control parameters designed based on its derivative function, thereby enhancing the output robust tracking accuracy of the variable structure hypersonic vehicles. The Lyapunov theory proves the system robust stability, semi-physical simulation verifies the validity of the proposed method and the superiority compared with the traditional method.