Platycarya strobilacea Sieb. et Zucc.: a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

J Pharm Pharmacol. 2022 May 20;74(5):646-659. doi: 10.1093/jpp/rgab110.

Abstract

Objectives: Platycarya strobilacea Sieb. et Zucc. is the dry infructescence of P. strobilacea, a Juglandaceae plant and is a traditional Chinese medicine with great development potential and utilization value. This study summarizes the research progress on the traditional uses, botany, phytochemistry, extraction methods, pharmacology and toxicology of Platycarya strobilacea Sieb. et Zucc., and provides potential therapeutic uses and drug development prospects for this plant.

Key findings: Phytochemical studies showed that this plant mainly contains volatile constituents, phenols, terpenoids and a carbohydrate. The pharmacological activity of Platycarya strobilacea Sieb. et Zucc. includes antibacterial and anti-inflammatory effects, anti-tumour effects and antioxidant effects. This plant is especially effective in the treatment of allergic rhinitis and chronic sinusitis.

Summary: In this review, the phytochemistry and pharmacological effects of Platycarya strobilacea Sieb. et Zucc. are described in detail, which will have guiding significance for the future development of this drug.

Keywords: Platycarya strobilacea Sieb. et Zucc; botany; pharmacology; phytochemistry; traditional uses.

Publication types

  • Review

MeSH terms

  • Botany*
  • Drugs, Chinese Herbal* / pharmacology
  • Ethnopharmacology
  • Juglandaceae*
  • Medicine, Chinese Traditional
  • Phytochemicals / pharmacology
  • Phytochemicals / therapeutic use
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use

Substances

  • Drugs, Chinese Herbal
  • Phytochemicals
  • Plant Extracts