Correlation between 18F-FDG dosage and SNR on various BMI patient groups tested in NEMA IEC PET phantom

Nazreen Waeleh; M Iqbal Saripan; Marianie Musarudin; Syamsiah Mashohor; Fathinul Fikri Ahmad Saad

doi:10.1016/j.apradiso.2021.109885

Correlation between ¹⁸F-FDG dosage and SNR on various BMI patient groups tested in NEMA IEC PET phantom

Appl Radiat Isot. 2021 Oct:176:109885. doi: 10.1016/j.apradiso.2021.109885. Epub 2021 Aug 4.

Authors

Nazreen Waeleh¹, M Iqbal Saripan², Marianie Musarudin³, Syamsiah Mashohor², Fathinul Fikri Ahmad Saad⁴

Affiliations

¹ Faculty of Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Faculty of Electronic and Computer Engineering, Universiti Teknikal Malaysia Melaka (UTeM), 76100 Durian Tunggal, Melaka, Malaysia. Electronic address: nazreen@utem.edu.my.
² Faculty of Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
³ School of Health Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
⁴ Centre for Diagnostic Nuclear Imaging, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.

PMID: 34385090
DOI: 10.1016/j.apradiso.2021.109885

Abstract

The present study was conducted to determine quantitatively the correlation between injected radiotracer and signal-to-noise ratio (SNR) based on differences in physiques and stages of cancer. Eight different activities were evaluated with modelled National Electrical Manufacturers Association (NEMA) of the International Electrotechnical Commission (IEC) PET's phantom with nine different tumour-to-background ratio (TBR). The findings suggest that the optimal value of dosage is required for all categories of patients in the early stages of cancer diagnosis.

Keywords: Body mass index; Monte Carlo N-Particle; Positron emission tomography; Tumor-to-background ratio.

MeSH terms

Body Mass Index*
Fluorine Radioisotopes / administration & dosage*
Humans
Neoplasms / diagnostic imaging
Phantoms, Imaging*
Signal-To-Noise Ratio

Substances

Fluorine Radioisotopes
Fluorine-18