License to LAP

Larissa D Cunha

doi:10.1016/j.chom.2021.07.010

License to LAP

Cell Host Microbe. 2021 Aug 11;29(8):1216-1217. doi: 10.1016/j.chom.2021.07.010.

Author

Larissa D Cunha¹

Affiliation

¹ Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: larissacunha@usp.br.

PMID: 34384524
DOI: 10.1016/j.chom.2021.07.010

Abstract

Engagement of LC3-associated phagocytosis (LAP) in response to the uptake of certain particles modulates innate immune responses. Now in Cell Host and Microbe, Akoumianaki et al. (2021) show how a regulatory role of IL-6 on LAP may be at the core of susceptibility to secondary infection during severe sepsis.

Publication types

Comment

MeSH terms

Autophagy*
Humans
Immunity, Innate
Microtubule-Associated Proteins
Phagocytosis
Phagosomes*

Substances

Microtubule-Associated Proteins