Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome

Leukemia. 2022 Feb;36(2):558-561. doi: 10.1038/s41375-021-01384-1. Epub 2021 Aug 11.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Down Syndrome / complications*
  • Intracellular Signaling Peptides and Proteins / genetics
  • Intracellular Signaling Peptides and Proteins / metabolism*
  • Leukemia, Myeloid, Acute / etiology
  • Leukemia, Myeloid, Acute / metabolism
  • Leukemia, Myeloid, Acute / pathology*
  • Mice
  • Mice, Inbred C57BL
  • Protein Serine-Threonine Kinases / antagonists & inhibitors*
  • Protein Serine-Threonine Kinases / genetics
  • Protein Serine-Threonine Kinases / metabolism

Substances

  • Intracellular Signaling Peptides and Proteins
  • Trib1 protein, mouse
  • Protein Serine-Threonine Kinases