Fibroblasts: The B's knees of follicular lymphoma

Krystal S A Lianos; Anne L Fletcher

doi:10.1016/j.immuni.2021.07.016

Fibroblasts: The B's knees of follicular lymphoma

Immunity. 2021 Aug 10;54(8):1628-1630. doi: 10.1016/j.immuni.2021.07.016.

Authors

Krystal S A Lianos¹, Anne L Fletcher²

Affiliations

¹ Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
² Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston B15 2TT, UK. Electronic address: anne.l.fletcher@monash.edu.

PMID: 34380060
DOI: 10.1016/j.immuni.2021.07.016

Abstract

Fibroblasts are the immunological architects of lymph nodes. In this issue of Immunity, Mourcin et al. describe the human tonsil fibroblast landscape and predicted T and B cell interactions. Transcriptomic changes in follicular lymphoma could provide untapped clinical targets.

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MeSH terms

Fibroblasts
Humans
Lymph Nodes
Lymphoma, Follicular*
Palatine Tonsil