Absence of Antibody Reponses and Severe COVID-19 in Patients on Hemodialysis Following mRNA Vaccination

Miriam B Michael; Siham M Mahgoub; Reiad Khan; Thomas A Mellman; Constance C Mere; Alem Mehari; Tammey J Naab; Uzoamake Nwagowugwu; Susan Ihaegwara; Celia J Maxwell

doi:10.1093/ofid/ofab337

Absence of Antibody Reponses and Severe COVID-19 in Patients on Hemodialysis Following mRNA Vaccination

Open Forum Infect Dis. 2021 Jun 27;8(8):ofab337. doi: 10.1093/ofid/ofab337. eCollection 2021 Aug.

Affiliations

¹ Department of Medicine, Howard University, Washington, DC, USA.
² Department of Psychiatry and Behavioral Sciences, Howard University, Washington, DC, USA.
³ Department of Pathology, Howard University, Washington, DC, USA.

Abstract

Inpatient dialysis patients cannot isolate, resulting in a higher rate of coronavirus disease 2019 (COVID-19) infections, with increased severity and higher mortality rate [1]. We present 2 African American dialysis patients who developed severe COVID-19 infections after vaccination. Both patients had not mounted antibody response to the COVID-19 vaccine or to hepatitis B vaccination.

Keywords: COVID-19; ESRD; hepatitis B; infection after COVID vaccination; nonrespondents; vaccination.