Rhino-orbital cerebral mucormycosis in a child with type 1 diabetes: A case report

SAGE Open Med Case Rep. 2021 Jul 31:9:2050313X211036781. doi: 10.1177/2050313X211036781. eCollection 2021.

Abstract

Rhino-orbital cerebral mucormycosis is a rare but potentially severe fungal infection in children with high rate of morbidity and mortality. In pediatric patients, uncontrolled diabetes mellitus is considered to be a predisposing factor only in 15% of cases. To prevent and reduce mortality rate of this severe disease, early diagnosis based on clinical findings and biopsy is highly recommended. Herein, we report a case of rhino-orbital cerebral mucormycosis in a 12-year-old girl with type 1 diabetes to demonstrate that a multimodal management approach, involving early surgery which consists in frequent endoscopic sinus debridement and appropriate antifungal therapy, is essential to effectively reduce the spread of infection and achieve effective outcome.

Keywords: Mucormycosis; antifungal medicine; children; surgery; type 1 diabetes.

Publication types

  • Case Reports