The diagnostic value of high-frequency ultrasound combined with color Doppler ultrasound versus surgical pathology in gallbladder polyps

Am J Transl Res. 2021 Jul 15;13(7):7990-7996. eCollection 2021.

Abstract

Objective: This study aimed to analyze the value of high-frequency ultrasound combined with color Doppler ultrasound in the diagnosis of gallbladder polyps.

Methods: A retrospective analysis was performed on 108 patients with gallbladder polyps, all of whom were examined by high-frequency ultrasound and color Doppler ultrasound with surgical or pathological findings as the gold standard.

Results: Taking surgical pathology findings as the gold standard, the diagnostic accuracy, sensitivity and specificity of high-frequency ultrasound for gallbladder polyps were 63.89%, 63.27%, and 70.00%, respectively. The diagnostic accuracy, sensitivity and specificity of color Doppler ultrasound were 74.07%, 73.47%, and 80.00%, respectively. The diagnostic accuracy, sensitivity and specificity of high-frequency ultrasound combined with color Doppler ultrasound were 91.67%, 90.82%, and 100.00%, respectively. The proportion of mulberry-like or papillary projections was 56.18% in 89 benign lesions diagnosed by high-frequency ultrasound combined with color Doppler ultrasound, the proportion of hyperechoic lesion was 47.19%, and the proportion of single lesion was 59.55%. The incidence rate of blood flow signal was 26.97% in 89 benign lesions, including 10 cases of punctiform blood flow signal, 9 cases of band-like blood flow signal and 5 cases of multiple stones in the lumen of the gallbladder.

Conclusion: High-frequency ultrasound combined with color Doppler ultrasound has high accuracy in the diagnosis of gallbladder polyps, and can yield better diagnostic results than either method, which can be used as an optional method for the diagnosis of gallbladder polyps.

Keywords: High-frequency ultrasound; color Doppler ultrasound; diagnosis; gallbladder polyps; pathology; surgery.