Diagnosis of Early Neurological Deterioration after Intravenous Thrombolysis for Patients with Cerebral Ischemic Stroke Using Compressed Sensing-Magnetic Resonance Imaging Algorithm

Contrast Media Mol Imaging. 2021 Jul 20:2021:2529936. doi: 10.1155/2021/2529936. eCollection 2021.

Abstract

This study was to explore the risk factors and prognosis of early neurological deterioration (END) after intravenous thrombolysis in patients with cerebral ischemic stroke (CIS) with the guidance of magnetic resonance imaging (MRI) under the compressed sensing-MRI (CSMRI) algorithm. 187 patients with CIS in the hospital were selected and grouped into a deterioration group and a control group according to whether they had END. The CSMRI algorithm was constructed and compared with digital television (DTV) algorithm and Bayesian compressed sensing (BCS) algorithm. It was found that the reconstruction time of CSMRI algorithm in platform I (1134.9 s) and platform II (2615.8 s) was visibly lower than that of DTV algorithm (2634.6 s, 3963.4 s) and BCS algorithm (5631.5 s, 7412.3 s), showing statistically obvious differences (P < 0.05). In addition, the reconstruction efficiency of the CSMRI algorithm was the best. After 4 hours of intravenous thrombolysis, the stroke scale score (12.3 scores) of the deterioration group was much higher than that of the control group (8.4 scores) (P < 0.05). The occlusion of responsible great vessel in the deterioration group (30 cases, 83.33%) was obviously higher in contrast to that in the control group (74 cases, 49%) (P < 0.05). Stroke scale score and occlusion of responsible great vessel were risk factors for EBD after intravenous thrombolysis.

MeSH terms

  • Algorithms*
  • Bayes Theorem
  • Brain Ischemia / pathology
  • Brain Ischemia / therapy*
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Ischemic Stroke / pathology
  • Ischemic Stroke / therapy*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / diagnosis*
  • Nervous System Diseases / etiology
  • Thrombolytic Therapy / adverse effects*
  • Treatment Outcome