Cancer Mechanisms and Emerging Therapies

Pharmaceutics. 2021 Jul 9;13(7):1045. doi: 10.3390/pharmaceutics13071045.

Diana Gulei¹, Alice Indini², Carmen Jerónimo^{3

4}, Cristina-Adela Iuga^{1

5}, Francesco Grossi⁶

¹ MEDFUTURE-Research Center for Advanced Medicine, "Iuliu-Hatieganu" University of Medicine and Pharmacy, Marinescu 23 Street/Louis Pasteur 4-6 Street, 400337 Cluj-Napoca, Romania.
² Medical Oncology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
³ Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
⁴ Department of Pathology and Molecular Immunology, Institute of Biomedical Sciences Abel Salazar, University of Porto (ICBAS-UP), Rua Jorge Viterbo Ferreira 228, 4050-513 Porto, Portugal.
⁵ Department of Pharmaceutical Analysis, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, Louis Pasteur Street 6, 400349 Cluj-Napoca, Romania.
⁶ Medical Oncology Unit, Department of Medicine and Surgery, University of Insubria, ASST dei Sette Laghi, 21100 Varese, Italy.

Abstract

Over the last decades, cancer has become one of the most relevant health issues at a worldwide level [...].