The association of COVID-19 antibody with in-hospital outcomes in COVID-19 infected patients

Toshiki Kuno; Matsuo So; Yoshihisa Miyamoto; Masao Iwagami; Mai Takahashi; Natalia N Egorova

doi:10.1002/jmv.27260

The association of COVID-19 antibody with in-hospital outcomes in COVID-19 infected patients

J Med Virol. 2021 Dec;93(12):6841-6844. doi: 10.1002/jmv.27260. Epub 2021 Aug 12.

Authors

Toshiki Kuno^{1

2}, Matsuo So¹, Yoshihisa Miyamoto³, Masao Iwagami⁴, Mai Takahashi¹, Natalia N Egorova⁵

Affiliations

¹ Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, New York City, New York, USA.
² Department of Cardiology, Montefiore Medical Center, Albert Einstein Medical College, New York City, New York, USA.
³ Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
⁴ Department of Health Services Research, University of Tsukuba, Tsukuba, Japan.
⁵ Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.

Abstract

We aimed to investigate whether hospitalizations of patients who tested positive for coronavirus disease 2019 (COVID-19) antibodies are associated with reduced in-hospital mortality. Of the 2459 patients admitted due to COVID-19 and tested for antibodies, 937 (38.1%) had positive tests. After adjustment for patient characteristics and treatments, patients with positive COVID-19 antibody test had lower in-hospital mortality compared with those with negative test results (odds ratio [OR]: 0.62; 95% confidential interval [95% CI] 0.46-0.83, p = 0.001). In conclusion, positive COVID-19 antibody test results were associated with the reduced risk of in-hospital mortality for COVID-19 patients.

Keywords: COVID-19; antibody; mortality.

MeSH terms

Aged
Antibodies, Viral / blood*
Antibodies, Viral / immunology*
COVID-19 / blood*
COVID-19 / immunology*
Female
Hospital Mortality
Hospitalization
Hospitals
Humans
Male
Middle Aged
Odds Ratio
Risk Factors

Substances

Antibodies, Viral