A Bioresorbable Dynamic Pressure Sensor for Cardiovascular Postoperative Care

Adv Mater. 2021 Oct;33(39):e2102302. doi: 10.1002/adma.202102302. Epub 2021 Aug 8.

Abstract

Bioresorbable electronics that can be absorbed and become part of the organism after their service life are a new trend to avoid secondary invasive surgery. However, the material limitation is a significant challenge. There are fewer biodegradable materials with pressure-sensitive properties. Here, a pressure sensor based on the triboelectric effect between bioabsorbable materials is reported. This effect is available in almost all materials. The bioresorbable triboelectric sensor (BTS) can directly convert ambient pressure changes into electrical signals. This device successfully identifies abnormal vascular occlusion events in large animals (dogs). The service life of the BTS reaches 5 days with a high service efficiency (5.95%). The BTS offers excellent sensitivity (11 mV mmHg-1 ), linearity (R2 = 0.993), and good durability (450 000 cycles). The antibacterial bioresorbable materials (poly(lactic acid)-(chitosan 4%)) for the BTS can achieve 99% sterilization. Triboelectric devices are expected to be applied in postoperative care as bioresorbable electronics.

Keywords: bioresorbable materials; dynamic pressure sensors; implantable devices; postoperative care; triboelectrics.

MeSH terms

  • Absorbable Implants*
  • Animals
  • Biocompatible Materials / chemistry
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / surgery*
  • Dogs
  • Dyspnea / physiopathology
  • Electronics
  • Mice
  • Monitoring, Physiologic / instrumentation*
  • Monitoring, Physiologic / methods
  • Polyesters / chemistry
  • Postoperative Care

Substances

  • Biocompatible Materials
  • Polyesters
  • poly(lactide)