Impact of quarterly professional-mode flash glucose monitoring in adults with type 2 diabetes in general practice (GP-OSMOTIC): Secondary psychological and self-care outcomes of a pragmatic, open-label, 12-month, randomised controlled trial

Jane Speight; E Holmes-Truscott; Sharmala Thuraisingam; Hanafi Mohamad Husin; Jo-Anne Manski-Nankervis; Katie De La Rue; Louise Ginnivan; Ralph Audehm; Malcolm Clark; Kamlesh Khunti; David O'Neal; John Furler; GP-OSMOTIC Study Group

doi:10.1016/j.diabres.2021.108994

Impact of quarterly professional-mode flash glucose monitoring in adults with type 2 diabetes in general practice (GP-OSMOTIC): Secondary psychological and self-care outcomes of a pragmatic, open-label, 12-month, randomised controlled trial

Diabetes Res Clin Pract. 2021 Sep:179:108994. doi: 10.1016/j.diabres.2021.108994. Epub 2021 Aug 4.

Affiliations

¹ School of Psychology, Deakin University, Geelong, Victoria, Australia; The Australian Centre for Behavioural Research in Diabetes, Diabetes Victoria, Melbourne, Victoria, Australia. Electronic address: jspeight@acbrd.org.au.
² School of Psychology, Deakin University, Geelong, Victoria, Australia; The Australian Centre for Behavioural Research in Diabetes, Diabetes Victoria, Melbourne, Victoria, Australia.
³ The Australian Centre for Behavioural Research in Diabetes, Diabetes Victoria, Melbourne, Victoria, Australia; Department of General Practice, University of Melbourne, Parkville, Victoria, Australia.
⁴ Department of General Practice, University of Melbourne, Parkville, Victoria, Australia.
⁵ Diabetes Research Centre, University of Leicester, UK.
⁶ Department of Medicine, University of Melbourne, Parkville, Victoria, Australia.

PMID: 34363864
DOI: 10.1016/j.diabres.2021.108994

Abstract

Aims: To investigate the impact of quarterly professional-mode flash glucose monitoring on psychological outcomes in adults with type 2 diabetes in primary care.

Methods: The GP-OSMOTIC trial randomised 299 adults with type 2 diabetes in 25 general practices to quarterly use of professional-mode flash glucose monitoring (sensor worn for 14 days; data discussed at clinic visit) or usual care. At baseline and 12 months, participants completed validated measures: general emotional well-being (WHO-5), diabetes-specific quality of life (DIDP), satisfaction with glucose monitoring (GME-Q), self-care activities (SDSCA) and perceived involvement in clinical care (PICS). Linear mixed-effects models examined between-group differences at 12 months.

Results: At 12 months, there were no clinically important between-arm differences in any secondary psychological or self-care outcomes. Per protocol analyses showed no clinically significant between-group differences.

Conclusions: The GP-OSMOTIC intervention had no significant impact, at 12 months, on general emotional well-being, diabetes-specific quality of life or satisfaction with glucose monitoring, suggesting no added psychological burden. Lack of positive impact on self-reported self-care activities or perceived involvement in clinical care may warrant closer attention to the fidelity of intervention delivery, the context (e.g. the nature of clinician-patient interactions) and/or the sensitivity of the measures, as these will help plan future studies.

Keywords: General practice; Glucose monitoring; Quality of life; Satisfaction; Type 2 diabetes; Well-being.

Publication types

Randomized Controlled Trial

MeSH terms

Adult
Blood Glucose
Blood Glucose Self-Monitoring
Diabetes Mellitus, Type 2* / therapy
General Practice*
Humans
Quality of Life
Self Care

Substances

Blood Glucose