A Review of 99mTc-labeled Tumor Metabolic Imaging Agents

Abstract

In recent years, with the development of nuclear medicine imaging technology, radionuclide- labeled tumor imaging agents have shown unique advantages in the early diagnosis of tumors. Due to the relatively low cost of SPECT in the clinic with the convenient preparation and suitable properties of ^99mTc, ^99mTc-labeled tumor metabolic imaging agents prepared based on principles of tumor metabolism have gained considerable attention. This article briefly introduces the progress in the research of ^99mTc-labeled glucose derivatives, amino acid derivatives, nucleotide derivatives, and other tumor metabolic imaging agents and proposes the prospects for the development of ^99mTclabeled tumor metabolic imaging agents.

Keywords: 99mTc; SPECT; amino acid derivatives; glucose derivatives; nucleotide derivatives; tumor metabolic imaging agent.