Aberrant Immunoglobulin Kappa Locus Rearrangement in a Patient with CARD11-Related B Cell Lymphocytosis

J Clin Immunol. 2021 Nov;41(8):1943-1945. doi: 10.1007/s10875-021-01114-3. Epub 2021 Aug 6.

Authors

Jackie L Ludgate¹, Robert J Weeks², Ian M Morison^{2

3}

Affiliations

¹ Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand. jackie.ludgate@otago.ac.nz.
² Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
³ Southern Community Laboratories, Dunedin, New Zealand.

PMID: 34355353
DOI: 10.1007/s10875-021-01114-3

No abstract available

Publication types

Case Reports
Letter

MeSH terms

B-Lymphocytes / immunology*
CARD Signaling Adaptor Proteins / genetics*
CARD Signaling Adaptor Proteins / immunology
Gain of Function Mutation
Gene Rearrangement
Guanylate Cyclase / genetics*
Guanylate Cyclase / immunology
Humans
Immunoglobulins / genetics*
Lymphocytosis / genetics*
Male
Middle Aged
NF-kappa B / immunology

Substances

CARD Signaling Adaptor Proteins
IgK
Immunoglobulins
NF-kappa B
CARD11 protein, human
Guanylate Cyclase