Oxygen-embedded quinoidal acene based semiconducting chromophore nanoprobe for amplified photoacoustic imaging

Baoli Yin; Yanpei Wang; Zhifei Ye; Shuangyan Huan; Guosheng Song

doi:10.1016/bs.mie.2021.06.034

Oxygen-embedded quinoidal acene based semiconducting chromophore nanoprobe for amplified photoacoustic imaging

Methods Enzymol. 2021:657:385-413. doi: 10.1016/bs.mie.2021.06.034. Epub 2021 Jul 12.

Authors

Baoli Yin¹, Yanpei Wang¹, Zhifei Ye¹, Shuangyan Huan², Guosheng Song³

Affiliations

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China.
² State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China. Electronic address: syhuan@hnu.edu.cn.
³ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China. Electronic address: songgs@hnu.edu.cn.

PMID: 34353496
DOI: 10.1016/bs.mie.2021.06.034

Abstract

In this chapter, we summarize the advantages of photoacoustic imaging and the current methods of enhancing photoacoustic. We then provide detailed procedures for the synthesis and characterization of a photoacoustic imaging molecule, Nano(O-Nonacene)-PEG, developed in our research group. At the same time, we proved that the incorporation of Zn_0.4Fe_2.6O₄ can enhance the photoacoustic imaging effect of Nano(O-Nonacene)-PEG. This provides a new material for photoacoustic imaging to guide tumor treatment.

Keywords: Enhancement; Imaging; Nanoparticles; Photoacoustic; Photothermal.

MeSH terms

Humans
Nanoparticles*
Neoplasms*
Oxygen
Photoacoustic Techniques*

Substances

Oxygen