Antioxidant and hemostatic properties of preparations from Asteraceae family and their chemical composition - Comparative studies

Biomed Pharmacother. 2021 Oct:142:111982. doi: 10.1016/j.biopha.2021.111982. Epub 2021 Aug 2.

Abstract

Asteraceae, known as sunflower family, is one of the largest flowering plants family around the world. Sunflower family contains numerous phytochemical compounds. The aim of this study was to describe phytochemical characteristics and investigate the effect of four sunflower vegetable preparations (extracts): chicory leaves (Cichorium intybus), green lettuce leaves (Lactuca sativa), red lettuce leaves (Lactuca sativa var. crispa) and sunchoke roots (Helianthus tuberosus) on different biomarkers of oxidative stress in human plasma in in vitro model. The antioxidant potential was also tested using the DPPH method. The phytochemical composition of the tested preparations was determined by UPLC-ESI-QTOF-MS. All the tested extracts demonstrated antioxidant activity in human plasma. We have observed chicory's and sunchoke's extracts had strongest antioxidant properties in the used models with human plasma. None of the tested vegetables changed ORAC and TAC in vitro. The obtained results suggest that sunflower vegetables might help to prevent oxidative stress related with cardiovascular diseases.

Keywords: Coagulation; Oxidative stress; Phytochemical composition; Plasma; Sunflower family; UPLC-ESI-QTOF-MS analysis.

Publication types

  • Comparative Study

MeSH terms

  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Asteraceae / chemistry*
  • Chromatography, High Pressure Liquid
  • Female
  • Hemostatics / isolation & purification
  • Hemostatics / pharmacology*
  • Humans
  • In Vitro Techniques
  • Male
  • Mass Spectrometry
  • Oxidative Stress / drug effects
  • Phytochemicals / chemistry
  • Phytochemicals / isolation & purification
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Leaves
  • Plant Roots

Substances

  • Antioxidants
  • Hemostatics
  • Phytochemicals
  • Plant Extracts