Incidence rate and risk factors of central line-associated bloodstream infections among neonates and children admitted to a tertiary care university hospital

Am J Infect Control. 2022 Jan;50(1):105-107. doi: 10.1016/j.ajic.2021.07.016. Epub 2021 Aug 1.

Abstract

Central-line associated bloodstream infection (CLABSI) is a common healthcare-associated infection in patients indwelling central venous catheter (CVC). This study examined the incidence rates, risk factors, and clinical outcomes of CLABSI among neonates (aged < 1 month) and children (aged ≥ 1 month) admitted to a tertiary care university hospital. An overall CLABSI incidence rate was 3.2 per 1,000 catheter-days. Number of CVC lumen and place of catheter insertion were a significant risk factor among our neonates and children, respectively. CLABSI prolonged hospitalization and increased hospital costs.

Keywords: Catheter-related bloodstream infection; Central venous catheterization; Clinical outcomes; Incidence; Newborns; Youth.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Bacteremia* / epidemiology
  • Bacteremia* / etiology
  • Catheter-Related Infections* / epidemiology
  • Catheter-Related Infections* / etiology
  • Catheterization, Central Venous* / adverse effects
  • Central Venous Catheters* / adverse effects
  • Child
  • Hospitalization
  • Hospitals
  • Humans
  • Incidence
  • Infant, Newborn
  • Retrospective Studies
  • Risk Factors
  • Sepsis* / epidemiology
  • Tertiary Healthcare