Locally advanced primary mediastinal atypical carcinoid successfully resected after neoadjuvant treatment: A case report

Thorac Cancer. 2021 Sep;12(17):2415-2419. doi: 10.1111/1759-7714.14091. Epub 2021 Aug 3.

Abstract

Neuroendocrine tumors (NETs) are epithelial neoplasms with predominant neuroendocrine differentiation that arise in most organs of the body. Mediastinal NETs are very rare, and account for no more than 5% of all mediastinal tumors. R0 surgery represents the milestone of treatment. Here, we describe a case of a locally advanced primary atypical carcinoid of the mediastinum. This was initially considered inoperable due to infiltration of a great vessel and was successfully resected after neoadjuvant treatment as a result of very extensive surgery. Only through an accurate preoperative diagnosis and good radiological planning is it possible to obtain satisfactory oncological results.

Keywords: NETs; atypical carcinoid; neuroendocrine tumor.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Carcinoid Tumor / drug therapy*
  • Carcinoid Tumor / surgery*
  • Combined Modality Therapy
  • Humans
  • Male
  • Mediastinal Neoplasms / drug therapy*
  • Mediastinal Neoplasms / surgery*
  • Neoadjuvant Therapy / methods*
  • Neuroendocrine Tumors / drug therapy
  • Neuroendocrine Tumors / surgery

Substances

  • Antineoplastic Agents