Bilateral Multifocal Choroiditis following COVID-19 Vaccination

Ocul Immunol Inflamm. 2021 May 19;29(4):753-757. doi: 10.1080/09273948.2021.1957123. Epub 2021 Aug 3.

Abstract

Purpose: To report a case of bilateral choroiditis following COVID-19 vaccination.Study Design: Case report.Results: A 34-year old male presented with visual loss one week after the second dose of COVID-19 vaccine. Examination showed large serous detachment of the macula in the right eye and severe choroidal thickening noted on ultrasonography in both eyes. The patient's condition improved rapidly with oral corticosteroids with significant resolution of the serous detachments within two weeks of initiating treatment and complete visual recovery subsequently.Conclusions: The onset of ocular symptoms starting within one week following vaccination suggests an inflammatory or autoimmune response to the vaccine. Ophthalmologists should consider the option of autoimmune and other inflammatory ocular problems, which may manifest as uveitis, following COVID-19 vaccination. Timely diagnosis and treatment with corticosteroids can result in good visual and structural outcome.

Keywords: COVID-19; COVID-19 vaccination; Covishield vaccine; choroiditis following vaccination; uveitis following vaccination.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • COVID-19 / prevention & control*
  • COVID-19 / virology
  • COVID-19 Vaccines / adverse effects*
  • Choroid / pathology
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Male
  • Multifocal Choroiditis / diagnosis
  • Multifocal Choroiditis / etiology*
  • SARS-CoV-2*
  • Tomography, Optical Coherence
  • Vaccination / adverse effects*
  • Visual Acuity*

Substances

  • COVID-19 Vaccines