Covalent organic frameworks-based smart materials for mitigation of pharmaceutical pollutants from aqueous solution

Abstract

Covalent organic frameworks (COFs) are an emergent group of crystalline porous materials that have gained incredible interest in recent years. With foreseeable controllable functionalities and structural configurations, the constructions and catalytic properties of these organic polymeric materials can be controlled to fabricate targeted materials. The specified monomer linkers and pre-designed architecture of COFs facilitate the post-synthetic modifications for introducing novel functions and useful properties. By virtue of inherent porosity, robust framework, well-ordered geometry, functionality, higher stability, and amenability to functionalization, COFs and COFs-based composites are regarded as prospective nanomaterials for environmental clean-up and remediation. This report spotlights the state-of-the-art advances and progress in COFs-based materials to efficiently mitigate pharmaceutical-based environmental pollutants from aqueous solutions. Synthesis approaches, structure, functionalization, and sustainability aspects of COFs are discussed. Moreover, the adsorptive and photocatalytic potential of COFs and their derived nanocomposites for removal and degradation of pharmaceuticals are thoroughly vetted. In addition to deciphering adsorption mechanism/isotherms, the stability, regeneratability and reproducibility are also delineated. Lastly, the outcomes are summed up, and new directions are proposed to widen the promise of COF-based smart materials in diverse fields.

Keywords: Adsorption isotherm; Covalent organic frameworks; Environmental pollutants; Functionalization; Pharmaceuticals; Photocatalysis; Reproducibility; Sustainability.