The obesity paradox in heart failure: What is the role of cardiorespiratory fitness?

Cleve Clin J Med. 2021 Aug 2;88(8):449-458. doi: 10.3949/ccjm.88a.20098.

Abstract

The obesity paradox describes a survival benefit for higher body mass index in patients with heart failure. But other factors like cardiorespiratory fitness may play a role in heart failure development, severity, and survival. Although more research is needed to better understand the relationships between body mass index and fitness in patients with heart failure, evidence indicates that recommending weight loss and an exercise program is appropriate for most patients.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Cardiorespiratory Fitness*
  • Heart Failure*
  • Humans
  • Obesity / complications
  • Prognosis
  • Risk Factors