Multimodal imaging in acute idiopathic blind spot enlargement syndrome

Abstract

Two cases are reported of acute idiopathic blind spot enlargement syndrome (AIBSE) that presented with peripapillary white spots in the fundus. AIBSE belongs to the acute zonal occult outer retinopathy (AZOOR) complex. Conditions of this AZOOR complex may overlap. Typically, in AIBSE, a peripapillary hyperautofluorescence is seen in the autofluorescence. En-face OCT angiography at the ellipsoid level showed hyper-reflective spots around the optic disk in both cases. One case showed a reversible enlargement of the blind spot in visual field. AZOOR complex is an inflammatory disorder that affects the outer retina, and can now be confirmed with structural optical coherence tomography. In the cases presented, there was a reversible severe loss of the outer retina.

Keywords: Acute idiopathic blind spot enlargement syndrome; Acute zonal occult outer retinopathy complex; Angiografía por tomografía de coherencia óptica; Autofluorescence; Autofluorescencia; Complejo de retinopatía aguda oculta zonal externa; En-face angiography; Optical coherence tomography angiography; Outer retina; Retina externa; Síndrome de aumento idiopático de mancha ciega; Tomografía de coherencia óptica.