Vacuoles in neutrophil precursors in VEXAS syndrome: diagnostic performances and threshold

Br J Haematol. 2021 Oct;195(2):286-289. doi: 10.1111/bjh.17679. Epub 2021 Aug 2.

Valentin Lacombe¹, Matthieu Prevost^{2

3}, Anne Bouvier^{2

3}, Sylvain Thépot^{3

4}, Floris Chabrun^{5

6}, Olivier Kosmider⁷, Carole Lacout¹, Annaelle Beucher^{2

3}, Christian Lavigne¹, Franck Geneviève^{2

3}, Geoffrey Urbanski^{1

6}

¹ Department of Internal Medicine and Clinical Immunology, Angers University Hospital, Angers, France.
² Laboratory of Haematology, Angers University Hospital, Angers, France.
³ Fédération Hospitalo-Universitaire 'Grand Ouest Against Leukemia' (FHU GOAL), Angers, France.
⁴ Department of Clinical Haematology, Angers University Hospital, Angers, France.
⁵ Department of Biochemistry and Molecular Biology, Angers University Hospital, Angers, France.
⁶ MitoLab Team, UMR CNRS 6015-INSERM U1083, MitoVasc Institute, SFR ICAT, Angers, France.
⁷ CNRS UMR8104, INSERM U1016, Laboratory of Haematology, Assistance Publique-Hôpitaux de Paris, Cochin Institute, Paris, France.

No abstract available

Keywords: VEXAS syndrome; autoinflammatory disorder; myelodysplastic syndromes; ubiquitin-activating enzymes; vacuoles.

Publication types