Aducanumab: a new phase in therapeutic development for Alzheimer's disease?

EMBO Mol Med. 2021 Aug 9;13(8):e14781. doi: 10.15252/emmm.202114781. Epub 2021 Aug 2.

Abstract

On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer's disease in almost 20 years-and notably, the first drug with a putative disease-modifying mechanism for the treatment of this devastating disorder, namely the removal of β-amyloid (or Aβ) plaques from the brain.

MeSH terms

  • Alzheimer Disease* / drug therapy
  • Amyloid beta-Peptides
  • Antibodies, Monoclonal, Humanized
  • Humans
  • Immunotherapy

Substances

  • Amyloid beta-Peptides
  • Antibodies, Monoclonal, Humanized
  • aducanumab