Found in translation-core network preservation across liver diseases and species

Montgomery Blencowe; Xia Yang

doi:10.1016/j.xcrm.2021.100347

Found in translation-core network preservation across liver diseases and species

Cell Rep Med. 2021 Jul 21;2(7):100347. doi: 10.1016/j.xcrm.2021.100347. eCollection 2021 Jul 20.

Authors

Montgomery Blencowe^{1

2}, Xia Yang^{1

2

3}

Affiliations

¹ Department Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
² Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
³ Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, CA, USA.

Abstract

Esmaili et al.¹ conducted co-expression network analysis to uncover core homeostatic modules critical to a broad spectrum of liver diseases in mouse and human. Perturbation state of core modules may underlie disease stages across species and serve as therapeutic targets.

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MeSH terms

Animals
Gene Regulatory Networks*
Liver Diseases* / therapy
Mice