Conductive Nanodiamond-Based Detection of Neurotransmitters: One Decade, Few Sensors

Saheed E Elugoke; Omolola E Fayemi; Abolanle S Adekunle; Thabo T I Nkambule; Bhekie B Mamba; Eno E Ebenso

doi:10.1021/acsomega.1c01534

Conductive Nanodiamond-Based Detection of Neurotransmitters: One Decade, Few Sensors

ACS Omega. 2021 Jul 13;6(29):18548-18558. doi: 10.1021/acsomega.1c01534. eCollection 2021 Jul 27.

Authors

Saheed E Elugoke¹, Omolola E Fayemi¹, Abolanle S Adekunle², Thabo T I Nkambule³, Bhekie B Mamba³, Eno E Ebenso³

Affiliations

¹ Department of Chemistry, School of Physical and Chemical Sciences, Faculty of Natural and Agricultural Sciences, North-West University (Mafikeng Campus), Private Bag X2046, Mmabatho 2735, South Africa.
² Department of Chemistry, Obafemi Awolowo University, Ile-Ife, PMB 220005, Nigeria.
³ Institute of Nanotechnology and Water Sustainability, College of Science, Engineering and Technology, University of South Africa, Johannesburg 1700, South Africa.

Abstract

Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp³ carbon atoms in its core and an sp² carbon adorned surface via edge defects or doping. Endogenous chemicals that provoke physiological responses in the human system called neurotransmitters (NTs) have been detected with several sensors with carbon-based nanomaterials. Nanodiamonds (NDs), another class of carbon nanomaterial, have shown the requisite surface area and electrocatalytic activity toward NTs in the past decade. Surprisingly, only a few electrochemical ND based NT sensors are available. This work briefly looked into the performance of the available sensors, NT and ND interactions, and the possible reason for data paucity on the subject matter.

Publication types

Review