Remote Monitoring of the QT Interval and Emerging Indications for Arrhythmia Prevention

Abstract

QT interval prolongation is a marker of increased risk for life-threatening arrhythmias, and needs to be promptly recognized. Many effective drugs, however, prolong QTc (QT interval corrected for heart rate) in genetically predisposed subjects. The possibility of remote monitoring and QTc measurement for up to 2 weeks, continuously providing physicians with real time data, allows life-saving interventions or changes in drug therapy. This applies especially to patients with the long QT syndrome and to those taking drugs blocking the IKr current and prolonging the QT interval. Patch monitors recording ECG traces continuously are available and contribute to effective arrhythmic prevention.

Keywords: Brugada syndrome; Cardiac arrhythmias; Deep learning machine; Idiopathic ventricular fibrillation; Long QT syndrome; Patches; Remote QT interval monitoring; e-Health.