Efficient parallel simulation of hemodynamics in patient-specific abdominal aorta with aneurysm

Comput Biol Med. 2021 Sep:136:104652. doi: 10.1016/j.compbiomed.2021.104652. Epub 2021 Jul 24.

Abstract

Surgical planning for aortic aneurysm repair is a difficult task. In addition to the morphological features obtained from medical imaging, alternative features obtained with computational modeling may provide additional useful information. Though numerical studies are noninvasive, they are often time-consuming, especially when we need to study and compare multiple repair scenarios, because of the high computational complexity. In this paper, we present a highly parallel algorithm for the numerical simulation of unsteady blood flows in the patient-specific abdominal aorta before and after the aneurysmic repair. We model the blood flow with the unsteady incompressible Navier-Stokes equations with different outlet boundary conditions, and solve the discretized system with a highly scalable domain decomposition method. With this approach, a high resolution simulation of a full-size adult aorta can be obtained in less than an hour, instead of days with older methods and software. In addition, we show that the parallel efficiency of the proposed method is near 70% on a parallel computer with 2, 880 processor cores.

Keywords: Abdominal aorta with aneurysm; Blood flow; Domain decomposition; Finite element; Fully implicit time integration; Parallel computing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aneurysm*
  • Aorta, Abdominal* / diagnostic imaging
  • Diagnostic Imaging
  • Hemodynamics
  • Humans