COVID-19, Acute Lymphoblastic Leukemia, and Down Syndrome: A Short Review and a Case Report

Ahmed Arafat; Dinara Sadykova; Ayrat Ziatdinov; Svetlana Senek; Natalya Samoilova; Tamara Makarova

doi:10.1159/000516442

COVID-19, Acute Lymphoblastic Leukemia, and Down Syndrome: A Short Review and a Case Report

Case Rep Oncol. 2021 Jul 1;14(2):1031-1039. doi: 10.1159/000516442. eCollection 2021 May-Aug.

Authors

Ahmed Arafat^{1

2}, Dinara Sadykova^{1

2}, Ayrat Ziatdinov^{1

2}, Svetlana Senek^{1

2}, Natalya Samoilova^{1

2}, Tamara Makarova^{1

2}

Affiliations

¹ Kazan State Medical University, Kazan, Russian Federation.
² Children's Republican Clinical Hospital, Kazan, Russian Federation.

Abstract

SARS-CoV-2 which causes COVID-19 has been a great challenge to treat and deal with; despite strict measures that had been implemented by governments and organizations, worrying rates of morbidity and mortality are still being reported. Although available data have expressed that moderate or even mild forms of the disease are expected amongst most pediatrics cases, minimal data are available on the prognosis and the disease's complications on the immunocompromised, especially oncology patients. We report a case of relapsed precursor B-cell acute lymphoblastic leukemia of a child with Down syndrome and COVID-19 and outline the treatment regimen that we used.

Keywords: Acute lymphoblastic leukemia; Corona virus disease 2019; Down syndrome; Infectious disease.

Publication types

Case Reports