Research on the Construction and Application of Breast Cancer-Specific Database System Based on Full Data Lifecycle

Front Public Health. 2021 Jul 12:9:712827. doi: 10.3389/fpubh.2021.712827. eCollection 2021.

Abstract

Relying on the Biomedical Big Data Center of West China Hospital, this paper makes an in-depth research on the construction method and application of breast cancer-specific database system based on full data lifecycle, including the establishment of data standards, data fusion and governance, multi-modal knowledge graph, data security sharing and value application of breast cancer-specific database. The research was developed by establishing the breast cancer master data and metadata standards, then collecting, mapping and governing the structured and unstructured clinical data, and parsing and processing the electronic medical records with NLP natural language processing method or other applicable methods, as well as constructing the breast cancer-specific database system to support the application of data in clinical practices, scientific research, and teaching in hospitals, giving full play to the value of medical big data of the Biomedical Big Data Center of West China Hospital.

Keywords: breast cancer; data governance; data security sharing; disease-specific database; knowledge graph; metadata.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms* / epidemiology
  • China / epidemiology
  • Databases, Factual
  • Electronic Health Records
  • Female
  • Humans
  • Natural Language Processing