Sporadic Creutzfeldt-Jakob disease should be considered in any case of rapid neuropsychiatric decline. While neuropathological examination of a brain biopsy specimen remains the only definitive diagnostic method and real-time quaking-induced conversion tests have simplified premortem diagnosis, careful evaluation of magnetic resonance imaging can provide readily accessible clues.
Keywords: Acute medicine; genetics; geriatric medicine; neurology; psychiatry.
© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.