Potentially Inappropriate Medication Use in the Elderly

Can J Aging. 2022 Jun;41(2):176-183. doi: 10.1017/S0714980821000234. Epub 2021 Jul 29.

Abstract

It is estimated that approximately half of adults, older than 65 years of age, have been prescribed potentially inappropriate medications (PIMs). This study's objective was to determine the prevalence of PIM use among older patients. Two retrospective chart reviews were performed on 200 and 164 older patients who underwent comprehensive geriatric assessments (CGAs) at outpatient geriatrics clinics at the Glenrose Rehabilitation Hospital (Glenrose) in 2012-13 and at the Misericordia Community Hospital (Misericordia) in 2016-17, respectively. Outcome measures included demographics; prevalence of PIM use; common PIMs used; whether PIM use was addressed, and if so, how; and total number of oral medications. At the Glenrose, the prevalence of PIM use was 45 per cent (90/200). Of the 90 patients who had used PIMs, 46.7 per cent (42/90) had at least one of their medications stopped or modified. At the Misericordia, the prevalence of PIM use was 57.3 per cent (94/164). Of the 94 patients who used PIMs, 47.9 per cent (45/94) had at least one of their medications stopped or modified. These results suggest that an increased awareness of PIM among physicians is needed to further decrease PIM use.

Keywords: Beers criteria; aging; comprehensive geriatric assessment; critères de Beers; deprescriptions; déprescription; inappropriate prescribing; liste de médicaments potentiellement inappropriés; médicaments potentiellement inappropriés; polypharmacie; polypharmacy; potentially inappropriate medication list; potentially inappropriate medications; prescription inappropriée; vieillissement; évaluation gériatrique complète.

MeSH terms

  • Aged
  • Humans
  • Inappropriate Prescribing*
  • Polypharmacy
  • Potentially Inappropriate Medication List*
  • Prevalence
  • Retrospective Studies