An Unusual Cause of Functional Mitral Stenosis: A Left Atrial Intimal Sarcoma

Jamie E Diamond; Michael Y Mi; Paul A VanderLaan; Louis Chu; Eli V Gelfand

doi:10.1016/j.jaccas.2021.02.043

An Unusual Cause of Functional Mitral Stenosis: A Left Atrial Intimal Sarcoma

JACC Case Rep. 2021 Apr 28;3(5):829-833. doi: 10.1016/j.jaccas.2021.02.043. eCollection 2021 May.

Authors

Jamie E Diamond¹, Michael Y Mi¹, Paul A VanderLaan², Louis Chu³, Eli V Gelfand¹

Affiliations

¹ Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
² Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
³ Department of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Primary cardiac tumors are rare, with an incidence of <0.1% in postmortem series; sarcomas comprise 75% of these. Cardiac sarcomas may be life-threatening at the time of presentation. We describe a left atrial intimal sarcoma presenting with constitutional symptoms, obstructive shock, and systemic emboli, and treated with proton beam therapy. (Level of Difficulty: Intermediate.).

Keywords: CT, computerized tomography; MDM2, mouse double minute 2 homolog; MRI, magnetic resonance imaging; acute heart failure; cancer; echocardiography; imaging; intimal sarcoma.

Publication types

Case Reports