Incessant Pericarditis With Recurrent Cardiac Tamponade as the Manifestation of Autoimmune Polyglandular Syndrome Type II

Ana V Marinho; Rui Baptista; Luís Cardoso; Patrícia M Alves; Sílvia Monteiro; Francisco Gonçalves; Lino Gonçalves

doi:10.1016/j.jaccas.2020.05.083

Incessant Pericarditis With Recurrent Cardiac Tamponade as the Manifestation of Autoimmune Polyglandular Syndrome Type II

JACC Case Rep. 2020 Aug 19;2(10):1536-1541. doi: 10.1016/j.jaccas.2020.05.083. eCollection 2020 Aug.

Authors

Ana V Marinho¹, Rui Baptista^{1

2

3

4}, Luís Cardoso⁵, Patrícia M Alves¹, Sílvia Monteiro¹, Francisco Gonçalves¹, Lino Gonçalves^{1

2

3

4}

Affiliations

¹ Cardiology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
² Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
³ Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.
⁴ Clinical Academic Centre of Coimbra (CACC), Coimbra, Portugal.
⁵ Endocrinology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Abstract

A 23-year-old man was admitted for acute pericarditis that evolved to cardiac tamponade and shock with need of emergent pericardiocentesis and inotropic support. Corticosteroid therapy was successful, but despite a gradual tapering, the patient relapsed. Incidentally, the patient developed hyperkalemia with hyponatremia. Subsequent hormonal measurements confirmed autoimmune polyglandular syndrome type-2. (Level of Difficulty: Intermediate.).

Keywords: AI, adrenal insufficiency; APS, autoimmune polyglandular syndrome; Abs, antibodies; Addison crisis; acute pericarditis; autoimmune polyangular syndrome type 2; cardiac tamponade.

Publication types

Case Reports