High-Grade Spindle Cell Sarcoma of the Heart: A Rare Cause of Mitral Valve Disease

Jay P Natarajan; Ashorne K Mahenthiran; Anil K Ranginani; Jo Mahenthiran

doi:10.1016/j.jaccas.2019.10.003

High-Grade Spindle Cell Sarcoma of the Heart: A Rare Cause of Mitral Valve Disease

JACC Case Rep. 2019 Nov 20;1(4):675-677. doi: 10.1016/j.jaccas.2019.10.003. eCollection 2019 Dec.

Authors

Jay P Natarajan¹, Ashorne K Mahenthiran², Anil K Ranginani³, Jo Mahenthiran³

Affiliations

¹ College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio.
² Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
³ Division of Cardiology, Community Heart and Vascular, Indianapolis, Indiana.

Abstract

A young female with pulmonary congestion suspected to be secondary to mitral valve disease with left atrial appendage thrombus was given therapy for heart failure and anticoagulation. Subsequent multimodality imaging with echocardiography and magnetic resonance imaging established an accurate but rare diagnosis of spindle cell sarcoma of the heart. (Level of Difficulty: Intermediate.).

Keywords: LA, left atrium; LV, left ventricle; OI, osteogenesis imperfecta; PV, pulmonary vein; RA, right atrium; RV, right ventricle; TEE, transesophageal echocardiography; TTE, transthoracic echocardiography; cancer; cardiac magnetic resonance; echocardiography; mitral valve; thrombus; treatment.