Quadravalvular Noninfectious Endocarditis

Peter P Vlismas; Jonas J Heymann; Charles C Marboe; Ulrich P Jorde; Daniel B Sims

doi:10.1016/j.jaccas.2019.07.026

Quadravalvular Noninfectious Endocarditis

JACC Case Rep. 2019 Sep 25;1(3):350-354. doi: 10.1016/j.jaccas.2019.07.026. eCollection 2019 Oct.

Authors

Peter P Vlismas¹, Jonas J Heymann², Charles C Marboe³, Ulrich P Jorde¹, Daniel B Sims¹

Affiliations

¹ Division of Cardiology, Montefiore Medical Center, Bronx, New York.
² Department of Pathology, Weill Cornell Medical Center, New York, New York.
³ Department of Pathology, Columbia University Medical Center, New York, New York.

Abstract

Nonbacterial thrombotic endocarditis is characterized by sterile thrombi on cardiac valves. This report describes the case of nonbacterial endocarditis without pathologic findings of fibrin or platelet deposition. Quadrivalvular endocarditis was found to be due to immunoglobulin M heavy chain deposition. This was a case of nonbacterial, nonthrombotic quadrivalvular endocarditis, which was termed noninfective endocarditis. (Level of Difficulty: Intermediate.).

Keywords: AV, atrioventricular; B-cell lymphoproliferative disorder; LAD, left anterior descending coronary artery; LHCDD, light and heavy chain deposition disease; NBTE, Nonbacterial thrombotic endocarditis; NIE, noninfective endocarditis; nonbacterial thrombotic endocarditis; noninfective endocarditis.

Publication types

Case Reports